SCHEMBL8220095

SCHEMBL8220095

CCCCCC1=C([Si](N[Si](C)(C)C)(c2ccccc2)c2ccccc2)CC=C1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.33
SIGMAR1 Q99720 1/20 0.31
DHFR P00374 1/20 0.30
KCNH3 Q9ULD8 1/20 0.30
HTR2A P28223 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8216453 0.99 DHFR (0.32) GPR84DHFRHTR2ADNM1
SCHEMBL8216356 0.99 DHFR (0.32) GPR84DHFRHTR2ADNM1
SCHEMBL8216410 0.96
SCHEMBL8215548 0.87 GPR84 (0.33) GPR84SIGMAR1DHFRKCNH3HTR2A
SCHEMBL8215587 0.86 NPC1 (0.33) GPR84DHFRHTR2ADNM1
SCHEMBL8215470 0.86 NPC1 (0.33) GPR84DHFRHTR2ADNM1
SCHEMBL8208020 0.85 KCNH3 (0.35) GPR84SIGMAR1DHFRKCNH3HTR2A
SCHEMBL8207977 0.84 KCNH3 (0.35) DHFRKCNH3HTR2ADNM1
SCHEMBL8218873 0.84 KCNH3 (0.35) DHFRKCNH3HTR2ADNM1
SCHEMBL8215717 0.84 SIGMAR1 (0.30) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed