Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 11/20 | 0.64 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9779790 | 0.99 | HCAR3 (0.62) | HCAR3CASP6TSHRAGTR1AGTR2 | |
| SCHEMBL7575190 | 0.99 | HCAR3 (0.62) | HCAR3CASP6TSHRAGTR1AGTR2 | |
| SCHEMBL27487118 | 0.95 | HCAR3 (0.63) | HCAR3CASP6TSHRAGTR1AGTR2 | |
| SCHEMBL6180268 | 0.89 | HCAR3 (0.64) | HCAR3CASP6TSHRAGTR1AGTR2 | |
| SCHEMBL11748103 | 0.87 | PDK1 (0.55) | HCAR3TSHRAGTR1AGTR2GAA | |
| SCHEMBL7402680 | 0.87 | CASP6 (0.58) | HCAR3CASP6TSHRLMNA | |
| SCHEMBL20757 | 0.86 | PDK1 (0.68) | HCAR3CASP6TSHRLMNAPDK1 | |
| SCHEMBL10757957 | 0.85 | HCAR3 (0.58) | HCAR3CASP6TSHRAGTR1AGTR2 | |
| SCHEMBL7998324 | 0.85 | VCAM1 (0.54) | HCAR3MAPTLMNAPDK1 | |
| SCHEMBL6476753 | 0.83 | TSHR (0.51) | HCAR3CASP6TSHRPLA2G4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520570-A1 | AMINOPYRIDINE COMPOUND | Ube Industries, Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| WO-2000056707-A1 | DIARYL THIOETHERS, COMPOSITIONS AND USES THEREOF | SEPRACOR, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259123-A1 | AMINOPYRIDINE COMPOUND | PTGIS, QDPR, PTGIR | HCAR3 1424/4885CASP6 4213/4885TSHR 4564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.