Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22649183 | 1.00 | HTR7 (0.39) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL19232108 | 0.98 | PSMD14 (0.41) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL21536775 | 0.98 | PSMD14 (0.41) | HTR7PSMD14HSP90AA1MMP2MC4R | |
| SCHEMBL9232425 | 0.94 | HTR7 (0.40) | HTR7ALDH1A1HPGDDRD2DRD4 | |
| SCHEMBL9278852 | 0.94 | HTR7 (0.40) | HTR7ALDH1A1HPGDDRD2DRD4 | |
| SCHEMBL6678858 | 0.89 | OPRM1 (0.44) | OPRM1SLC2A1 | |
| SCHEMBL9137197 | 0.87 | SLC2A1 (0.44) | OPRM1SLC2A1 | |
| SCHEMBL6684351 | 0.87 | SLC2A1 (0.44) | OPRM1SLC2A1 | |
| SCHEMBL21503575 | 0.85 | ALDH1A1 (0.44) | HTR7ALDH1A1HPGDSLC6A2SLC6A3 | |
| SCHEMBL18286641 | 0.85 | ALDH1A1 (0.44) | HTR7ALDH1A1HPGDSLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033447-A1 | AZETIDINE AND AZETIDONE DERIVATIVES USEFUL IN TREATING PAIN AND DISORDERS OF LIPID METABOLISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |