Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219210 | 0.88 | HTT (0.38) | HTTRAB9AL3MBTL1PIN1ALDH1A1 | |
| SCHEMBL8219165 | 0.73 | ALDH1A1 (0.55) | HTTRAB9AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL8219402 | 0.65 | L3MBTL1 (0.66) | HTTRAB9AL3MBTL1PIN1ALDH1A1 | |
| SCHEMBL23443667 | 0.65 | PARP1 (0.42) | RAB9AL3MBTL1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL20978554 | 0.57 | PDE10A (0.35) | L3MBTL1ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL25010300 | 0.57 | ALDH1A1 (0.71) | HTTRAB9AL3MBTL1ALDH1A1POLB | |
| SCHEMBL10551003 | 0.57 | ASAH1 (0.47) | RAB9AL3MBTL1ALDH1A1KDM4ECASP1 | |
| SCHEMBL362857 | 0.56 | ALDH1A1 (0.36) | HTTRAB9AALDH1A1KDM4EMAPT | |
| SCHEMBL18698090 | 0.56 | HTR2A (0.41) | L3MBTL1ALDH1A1POLBMAPTHSD17B10 | |
| SCHEMBL14160917 | 0.55 | ALDH1A1 (0.41) | RAB9AALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023357-A1 | HETEROCYCLIC DERIVATIVES BINDING TO THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR (PBR) | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2008-02-28 | — | — | WO | disclosed |