Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13502461 | 0.79 | CYP1A2 (0.54) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL13502531 | 0.77 | KMT2A (0.62) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL3587923 | 0.77 | KMT2A (0.54) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL8219165 | 0.75 | ALDH1A1 (0.55) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL3580872 | 0.75 | ALDH1A1 (0.54) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL28009020 | 0.74 | CASR (0.60) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL27685271 | 0.72 | ALDH1A1 (0.61) | HTTALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL6313895 | 0.71 | ALDH1A1 (0.64) | L3MBTL1RAB9AHTTCYP1A2CYP2C9 | |
| SCHEMBL29764078 | 0.70 | KMT2A (0.65) | RAB9AALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL1463333 | 0.70 | KMT2A (0.65) | RAB9AALDH1A1SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008023357-A1 | HETEROCYCLIC DERIVATIVES BINDING TO THE PERIPHERAL-TYPE BENZODIAZEPINE RECEPTOR (PBR) | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2008-02-28 | — | — | WO | disclosed |