Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22197948 | 0.83 | HTR3A (0.46) | ADKMAPTKMT2APIK3CAMTOR | |
| SCHEMBL14130867 | 0.81 | MAPT (0.45) | ADKMAPTPIK3CAMTOR | |
| SCHEMBL14130936 | 0.81 | PLD1 (0.46) | ADKALDH1A1HSD17B10KDM4EMAPT | |
| SCHEMBL585663 | 0.81 | ADK (0.56) | ADKALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL1570081 | 0.81 | ADK (0.56) | ADKALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL15541360 | 0.81 | ADK (0.56) | ADKALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL523894 | 0.81 | ADK (0.56) | ADKALDH1A1HSD17B10HPGDKDM4E | |
| SCHEMBL22197978 | 0.78 | MAPT (0.42) | ADKKDM4EGAAMAPTPIK3CA | |
| SCHEMBL22197947 | 0.77 | DRD2 (0.43) | KDM4EGAAMAPTPIK3CAMTOR | |
| SCHEMBL1432681 | 0.76 | ADK (0.57) | ADKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008025694-A1 | INHIBITORS FOR GLYT-1 | F. HOFFMANN-LA ROCHE AG (CH) | 2008-03-06 | — | — | WO | disclosed |