Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8196335 | 0.90 | LMNA (0.38) | NAMPTIKBKBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL7982467 | 0.80 | SLC6A2 (0.37) | NAMPTSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL7982471 | 0.80 | SLC6A2 (0.37) | NAMPTSLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8198968 | 0.79 | IKBKB (0.44) | NAMPTIKBKBKMT2ACYP3A4CYP2C9 | |
| SCHEMBL8199078 | 0.78 | HTR1A (0.42) | NAMPTIKBKBSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8195688 | 0.78 | IKBKB (0.43) | NAMPTIKBKBKMT2ACYP3A4CYP2C9 | |
| SCHEMBL8195918 | 0.76 | IKBKB (0.37) | NAMPTIKBKBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8195627 | 0.75 | IKBKB (0.46) | NAMPTIKBKBMEN1KMT2ACYP3A4 | |
| SCHEMBL8195516 | 0.74 | IKBKB (0.63) | NAMPTIKBKBMEN1KMT2ACYP3A4 | |
| SCHEMBL8200614 | 0.71 | IKBKB (0.38) | NAMPTIKBKBMEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |