Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982471 | 1.00 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3NAMPTADRB2 | |
| SCHEMBL8196333 | 0.90 | ADRB2 (0.36) | NAMPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL8196331 | 0.90 | ADRB2 (0.36) | NAMPTADRB2ADRB1ADRB3LMNA | |
| SCHEMBL8218893 | 0.80 | NAMPT (0.37) | SLC6A2SLC6A4SLC6A3NAMPTCYP1A2 | |
| SCHEMBL7978001 | 0.79 | LATS1 (0.37) | NAMPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7977997 | 0.79 | LATS1 (0.37) | NAMPTCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL7979658 | 0.78 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3ADRB2ADRB1 | |
| SCHEMBL7979656 | 0.78 | HTR1A (0.42) | SLC6A2SLC6A4SLC6A3ADRB2ADRB1 | |
| SCHEMBL8195916 | 0.76 | HRH4 (0.36) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 | |
| SCHEMBL8195910 | 0.76 | HRH4 (0.36) | ADRB2ADRB1ADRB3CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |