Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055008 | 0.84 | MAPT (0.53) | MAPTMAOBMAOAHIF1AMEN1 | |
| SCHEMBL11777480 | 0.74 | HIF1A (0.50) | MAPTHIF1AMEN1KMT2ACYP1A2 | |
| SCHEMBL5179423 | 0.74 | CYP1A2 (0.55) | MAPTMAOBMAOAHIF1AMEN1 | |
| SCHEMBL31438448 | 0.74 | HDAC3 (0.47) | MAPTMAOBMAOAHIF1AMEN1 | |
| SCHEMBL7988500 | 0.74 | RAB9A (0.65) | MAPTMAOBHIF1AMEN1KMT2A | |
| SCHEMBL802584 | 0.74 | HIF1A (0.74) | MAPTMAOBHIF1AMEN1KMT2A | |
| SCHEMBL11513654 | 0.74 | KMT2A (0.72) | MAPTMAOBMEN1KMT2ACYP1A2 | |
| SCHEMBL11080258 | 0.74 | MAPT (0.52) | MAPTHIF1AMEN1KMT2AHTT | |
| SCHEMBL21799637 | 0.74 | CFD (0.47) | MAPTMAOBMAOAHIF1AMEN1 | |
| SCHEMBL31246336 | 0.74 | CYP1A2 (0.55) | MAPTMAOBMAOAHIF1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136995-A | Process for producing aminosilane compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-24 | — | — | US | disclosed |