SCHEMBL821907

SCHEMBL821907

Cc1nc(NC(=O)c2ccccc2Cl)nc(NC(=O)c2ccccc2Cl)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.58
SMN1; SMN2 Q16637 4/20 0.58
CYP2C19 P33261 3/20 0.58
NPC1 O15118 3/20 0.58
CYP1A2 P05177 2/20 0.58
HPGD P15428 3/20 0.56
MAPT P10636 3/20 0.56
KMT2A Q03164 2/20 0.56
F2 P00734 1/20 0.56
JAK2 O60674 1/20 0.54
TYK2 P29597 1/20 0.54
POLB P06746 2/20 0.53
LMNA P02545 1/20 0.52
ALDH1A1 P00352 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51
SMO Q99835 1/20 0.50
MEN1 O00255 1/20 0.50
CYP11B2 P19099 1/20 0.50
GRM4 Q14833 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10310551 0.88 JAK2 (0.56) RAB9ASMN1; SMN2CYP2C19NPC1CYP1A2
SCHEMBL2623148 0.83 HPGD (0.59) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL12974727 0.83 GRM4 (0.51) RAB9ASMN1; SMN2CYP2C19NPC1HPGD
SCHEMBL822334 0.78 RXFP1 (0.64) RAB9ASMN1; SMN2NPC1MAPTKMT2A
SCHEMBL2623093 0.76 L3MBTL1 (0.64) RAB9ASMN1; SMN2NPC1CYP1A2HPGD
SCHEMBL27804869 0.75 KMT2A (0.53) RAB9ASMN1; SMN2CYP2C19NPC1CYP1A2
SCHEMBL822047 0.73 RAB9A (0.58) RAB9ASMN1; SMN2NPC1HPGDMAPT
SCHEMBL8055108 0.73 SMO (0.71) RAB9ASMN1; SMN2CYP2C19NPC1CYP1A2
SCHEMBL5653845 0.73 HPGD (0.54) RAB9ASMN1; SMN2CYP2C19NPC1CYP1A2
SCHEMBL2623094 0.73 ADORA1 (0.60) RAB9ASMN1; SMN2NPC1CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-9151883-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-10-06 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8937696-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-01-20 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-8906475-B2 Cellulose acylate film, retardation film, polarizer and liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-12-09 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-20140318413-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2014-10-30 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-8792071-B2 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2014-07-29 US disclosed
US-20120177848-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-07-12 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-8158220-B2 Cellulose acylate film, retardation film, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-17 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20120018685-A1 Optical film, retardation film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-01-26 US disclosed
US-20110255037-A1 Cellulose acylate film, its production method, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-10-20 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110076423-A1 CELLULOSE ACYLATE FILM, RETARDATION FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110073007-A1 HUMIDITY DEPENDENCE IMPROVER FOR POLYMER FILM, POLYMER FILM, PROTECTIVE FILM FOR POLARIZER, RETARDATION FILM, POLARIZER, AND LIQUID CRYSTAL DISPLAY DEVICE CNKSR1, C1R, PNISR RAB9A 2981/4885SMN1; SMN2 3112/4885CYP2C19 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.