Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8227226 | 0.91 | HTR2C (0.44) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL8224316 | 0.88 | HTR2C (0.48) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL8219624 | 0.76 | CSNK2A1 (0.41) | HTR2CHTR2ACSNK2A1HTR2BMEN1 | |
| SCHEMBL8227807 | 0.75 | ADRA2A (0.37) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL8223057 | 0.75 | L3MBTL1 (0.44) | HSD17B10MEN1KMT2ATSHRMAPT | |
| SCHEMBL28826984 | 0.75 | CSNK2A1 (0.51) | HTR2CHTR2ACSNK2A1HTR2BMEN1 | |
| SCHEMBL28627196 | 0.73 | HTR2C (0.55) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL23226950 | 0.72 | HTR2C (0.55) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL16923834 | 0.72 | HTR2C (0.43) | HTR2CHTR2AADRA2AADRA2BADRA2C | |
| SCHEMBL28250971 | 0.72 | CYP3A4 (0.42) | HTR2CHTR2AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140274-A | Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-31 | — | — | US | disclosed |