SCHEMBL8219624

SCHEMBL8219624

CC=COc1c(OCCC)ccc(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.41
MAPT P10636 4/20 0.34
ALDH1A1 P00352 3/20 0.34
KMT2A Q03164 3/20 0.34
POLB P06746 2/20 0.34
MEN1 O00255 2/20 0.34
HTT P42858 2/20 0.34
KDM4E B2RXH2 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
GAA P10253 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
ATM Q13315 1/20 0.34
HTR2C P28335 4/20 0.34
HTR2B P41595 2/20 0.34
GPR55 Q9Y2T6 1/20 0.34
PDE7A Q13946 1/20 0.34
PDE7B Q9NP56 1/20 0.34
HTR2A P28223 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8227228 0.91 THRB (0.36) CSNK2A1MAPTALDH1A1KMT2AMEN1
SCHEMBL8224319 0.88 ALDH1A1 (0.38) MAPTALDH1A1POLBHTTATM
SCHEMBL8219622 0.76 HTR2C (0.46) CSNK2A1MAPTALDH1A1KMT2APOLB
SCHEMBL8227803 0.75 GLA (0.36) MAPTALDH1A1KDM4EGAAATM
SCHEMBL8223061 0.75 L3MBTL1 (0.44) MAPTALDH1A1KDM4ETP53NPC1
SCHEMBL28826984 0.75 CSNK2A1 (0.51) CSNK2A1MAPTALDH1A1KMT2APOLB
SCHEMBL8225175 0.69 CYP1A2 (0.35) MAPTALDH1A1KMT2APOLBMEN1
SCHEMBL8222943 0.69 CYP1A2 (0.35) MAPTALDH1A1HTTKDM4EGAA
SCHEMBL9636247 0.68 ALDH1A1 (0.35) MAPTALDH1A1KMT2APOLBMEN1
SCHEMBL8227226 0.68 HTR2C (0.44) MAPTALDH1A1KMT2AMEN1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140274-A Dihalopropene compounds, their use as insecticides/acaricides and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-31 US disclosed