Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | AQP1 | P29972 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964730 | 0.82 | AQP1 (0.47) | HTR2AHTR2CHTR2BAQP1TAAR1 | |
| SCHEMBL4960764 | 0.82 | AQP1 (0.47) | HTR2AHTR2CHTR2BAQP1TAAR1 | |
| SCHEMBL4959837 | 0.82 | AQP1 (0.47) | HTR2AHTR2CHTR2BAQP1TAAR1 | |
| SCHEMBL8225498 | 0.80 | AQP1 (0.43) | CA2HTR2AHTR2CHTR2BAHR | |
| SCHEMBL6104448 | 0.79 | DPP4 (0.40) | HTR2AHTR2CHTR2BAQP1DPP4 | |
| SCHEMBL8225826 | 0.77 | CA2 (0.50) | CA2HTR2AHTR2CHTR2BAQP1 | |
| SCHEMBL4961501 | 0.77 | CA2 (0.50) | CA2HTR2AHTR2CHTR2BAQP1 | |
| SCHEMBL8220872 | 0.77 | CA2 (0.50) | CA2HTR2AHTR2CHTR2BAQP1 | |
| SCHEMBL4960551 | 0.74 | AQP1 (0.43) | HTR2AHTR2CHTR2BAQP1DPP4 | |
| SCHEMBL4964618 | 0.73 | AQP1 (0.37) | CA2HTR2AHTR2CHTR2BAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | HTR2C, HTR1D, HTR1A | CA2 4153/4885HTR2A 7/4885HTR2C 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.