Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079787 | 0.98 | ACHE (0.35) | ACHEKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL18883571 | 0.94 | MGAM (0.34) | ACHE | |
| SCHEMBL17126889 | 0.92 | KDM4E (0.37) | ACHEKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL13686222 | 0.90 | EPHX1 (0.35) | ACHEKDM4EMAPK1HIF1ATSHR | |
| SCHEMBL13010535 | 0.85 | ACHE (0.38) | ACHETSHR | |
| SCHEMBL13144569 | 0.84 | ALDH1A1 (0.41) | ACHEKDM4ETSHR | |
| SCHEMBL15293386 | 0.81 | EPHX1 (0.40) | ACHETSHR | |
| SCHEMBL13144606 | 0.80 | HTT (0.33) | TSHR | |
| SCHEMBL18895910 | 0.80 | ACHE (0.42) | ACHETSHR | |
| SCHEMBL13010568 | 0.79 | ACHE (0.32) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9695268-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2017-07-04 | — | — | US | disclosed |
| US-20150105530-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LTD (AU) | 2015-04-16 | — | — | US | disclosed |
| US-8962786-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LTD (AU) | 2015-02-24 | — | — | US | disclosed |
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
| US-7964696-B2 | Chain extenders | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-06-21 | — | — | US | disclosed |
| US-20090175921-A1 | Chain Extenders | POLYNOVO BIOMATERIALS PTY LIMITED | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | ACHE 4438/4885KDM4E 1903/4885MAPK1 1917/4885 |
| US-20090175921-A1 | Chain Extenders | UMPS, PUF60, SMC1A | ACHE 4444/4885KDM4E 1948/4885MAPK1 1706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.