SCHEMBL10079787

SCHEMBL10079787

COCOC(=O)NCNC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ACHE P22303 12/20 0.35
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.31
ALDH1A1 P00352 2/20 0.31
NPSR1 Q6W5P4 1/20 0.30
MTNR1A P48039 1/20 0.30
MTNR1B P49286 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
MGAM O43451 1/20 0.30
GAA P10253 1/20 0.30
SI P14410 1/20 0.30
MGAM2 Q2M2H8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL822121 0.98 ACHE (0.34) ACHEKDM4EMAPK1HIF1ATSHR
SCHEMBL18883571 0.93 MGAM (0.34) ACHEMGAMGAASIMGAM2
SCHEMBL17126889 0.89 KDM4E (0.37) ACHEKDM4EMAPK1HIF1ATSHR
SCHEMBL13686222 0.88 EPHX1 (0.35) ACHEKDM4EMAPK1HIF1ATSHR
SCHEMBL13010535 0.87 ACHE (0.38) ACHETSHR
SCHEMBL18895910 0.82 ACHE (0.42) ACHETSHRALDH1A1MTNR1AMTNR1B
SCHEMBL13144569 0.82 ALDH1A1 (0.41) ACHEKDM4ETSHRALDH1A1SMN1; SMN2
SCHEMBL12743892 0.80 EPHX1 (0.41) KDM4EMAPK1HIF1ATSHRALDH1A1
SCHEMBL19958891 0.79 KDM4E (0.30) KDM4EMAPK1HIF1A
SCHEMBL17886024 0.79 ACHE (0.42) ACHETSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160074560-A1 ANTIMICROBIAL CATHETERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-03-17 US disclosed
US-9101955-B2 Active energy ray-curable ink composition, inkjet recording method, decorative sheet, decorative sheet molded product, method for producing in-mold molded product, and in-mold molded product FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8940813-B2 Actinic radiation-curing type ink composition, inkjet recording method, decorative sheet, decorative sheet molded product, process for producing in-mold molded article, and in-mold molded article FUJIFILM CORPORATION (JP) 2015-01-27 US disclosed
US-20130295342-A1 ACTIVE ENERGY RAY-CURABLE INK COMPOSITION, INKJET RECORDING METHOD, DECORATIVE SHEET, DECORATIVE SHEET MOLDED PRODUCT, METHOD FOR PRODUCING IN-MOLD MOLDED PRODUCT, AND IN-MOLD MOLDED PRODUCT FUJIFILM CORPORATION (JP) 2013-11-07 US disclosed
US-20130260092-A1 ACTINIC RADIATION-CURING TYPE INK COMPOSITION, INKJET RECORDING METHOD, DECORATIVE SHEET, DECORATIVE SHEET MOLDED PRODUCT, PROCESS FOR PRODUCING IN-MOLD MOLDED ARTICLE, AND IN-MOLD MOLDED ARTICLE FUJIFILM CORPORATION (JP) 2013-10-03 US disclosed
US-20130017161-A1 Cosmetic Compositions with Silicone Resin Polymers REVLON (US) 2013-01-17 US disclosed
US-20120045493-A1 Solid Cosmetic Composition with Structurant and Electrolyte Solution CITICORP USA, INC., AS COLLATERAL AGENT 2012-02-23 US disclosed
US-7795467-B1 Bioabsorbable, biobeneficial polyurethanes for use in medical devices ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2010-09-14 US disclosed
US-20080152606-A1 Compositions for Treating Keratinous Surfaces REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-06-26 US disclosed
US-7341743-B2 Color cosmetic compositions REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-03-11 US disclosed
US-20080050328-A1 Cosmetic Compositions with Silicone Resin Polymers REVLON CONSUMER PORDUCTS CORPORATION (US) 2008-02-28 US disclosed
US-20080044367-A1 Cosmetic Compositions with Film Forming Polymer REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-02-21 US disclosed
US-20080031834-A1 Cosmetic Compositions REVLON CONSUMER PRODUCTS CORPORATION (US) 2008-02-07 US disclosed
US-20080019932-A1 Color Cosmetic Compositions CITICORP USA, INC. 2008-01-24 US disclosed
US-20070274939-A1 Color Cosmetic Compositions CITICORP USA, INC. 2007-11-29 US disclosed
US-20070243143-A1 Cosmetic Compositions With Backbiting Silicone Polymers CITICORP USA, INC. 2007-10-18 US disclosed
US-20070243220-A1 Cosmetic Compositions CITICORP USA, INC. 2007-10-18 US disclosed
US-20070166247-A1 Method for improving moisturization and hydrating properties lip products CITICORP USA, INC. 2007-07-19 US disclosed
US-20070020216-A1 Compositions for Treating Keratinous Surfaces REVLON CONSUMER PRODUCTS CORPORATION 2007-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120045493-A1 Solid Cosmetic Composition with Structurant and Electrolyte Solution LCT, CUTA, DLST ACHE 887/4885KDM4E 1760/4885MAPK1 1206/4885
US-20070166247-A1 Method for improving moisturization and hydrating properties lip products LIPA, LIPE, LPL ACHE 1748/4885KDM4E 2412/4885MAPK1 2994/4885
US-20080031834-A1 Cosmetic Compositions DPM1, DDT, DUS2 ACHE 2941/4885KDM4E 752/4885MAPK1 4076/4885
US-20130017161-A1 Cosmetic Compositions with Silicone Resin Polymers TSN, MMS19, REV1 ACHE 3040/4885KDM4E 1422/4885MAPK1 3795/4885
US-20070020216-A1 Compositions for Treating Keratinous Surfaces KRT18, FN1, HKDC1 ACHE 2084/4885KDM4E 1171/4885MAPK1 1052/4885
US-20080044367-A1 Cosmetic Compositions with Film Forming Polymer CUTA, KRT18, DSG1 ACHE 1239/4885KDM4E 233/4885MAPK1 3431/4885
US-20070274939-A1 Color Cosmetic Compositions CUTA, TYR, PDS5A ACHE 396/4885KDM4E 3416/4885MAPK1 1469/4885
US-20080050328-A1 Cosmetic Compositions with Silicone Resin Polymers TSN, MMS19, REV1 ACHE 3040/4885KDM4E 1422/4885MAPK1 3795/4885
US-20070243220-A1 Cosmetic Compositions CUTA, PARG, PCBP1 ACHE 2497/4885KDM4E 3977/4885MAPK1 4761/4885
US-20080019932-A1 Color Cosmetic Compositions CUTA, TYR, PDS5A ACHE 396/4885KDM4E 3416/4885MAPK1 1469/4885
US-20160074560-A1 ANTIMICROBIAL CATHETERS PARG, GMNN, AMPD2 ACHE 4146/4885KDM4E 3692/4885MAPK1 2028/4885
US-20070243143-A1 Cosmetic Compositions With Backbiting Silicone Polymers MMS19, LSM14A, PCBP1 ACHE 2802/4885KDM4E 3223/4885MAPK1 2082/4885
US-20080152606-A1 Compositions for Treating Keratinous Surfaces KRT18, PLOD3, GLA ACHE 465/4885KDM4E 3040/4885MAPK1 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.