SCHEMBL822281

SCHEMBL822281

[CH2]C(=C)N(CC=C)CC=C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
GRIN2D O15399 1/20 0.31
GRIN3B O60391 1/20 0.31
GRIN1 Q05586 1/20 0.31
GRIN2A Q12879 1/20 0.31
GRIN2B Q13224 1/20 0.31
GRIN2C Q14957 1/20 0.31
GRIN3A Q8TCU5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2540205 0.73 ALDH1A1 (0.48) ALDH1A1CYP1A2SMN1; SMN2TSHRGRIN2D
SCHEMBL8098659 0.73 ALDH1A1 (0.48) ALDH1A1CYP1A2SMN1; SMN2TSHRGRIN2D
SCHEMBL611476 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2SMN1; SMN2TSHR
SCHEMBL11498930 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2SMN1; SMN2TSHR
SCHEMBL822282 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2SMN1; SMN2TSHR
SCHEMBL10972334 0.73 ALDH1A1 (0.42) ALDH1A1CYP1A2SMN1; SMN2TSHRGRIN2D
SCHEMBL3258454 0.73 ALDH1A1 (0.54) ALDH1A1CYP1A2SMN1; SMN2
SCHEMBL3360577 0.71 ALDH1A1 (0.41) ALDH1A1CYP1A2SMN1; SMN2
SCHEMBL6685776 0.71 ALDH1A1 (0.41) ALDH1A1CYP1A2SMN1; SMN2
SCHEMBL22591335 0.69 ALDH1A1 (0.39) ALDH1A1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059539-B1 USE OF A GLYOXYLATED VINYLAMIDE POLYMER AS DRY AND WET STRENGTH AID FOR PAPER BASF SE (DE) 2011-11-16 EP claimed
CN-110268114-B High molecular weight temporary wet strength resins for paper 索理思科技开曼公司 2022-12-13 CN disclosed
CN-113785029-A Compositions and methods for increasing wet and dry paper strength 索理思科技开曼公司 2021-12-10 CN disclosed
EP-3130615-B1 GLYOXALATION OF VINYLAMIDE POLYMER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2021-03-10 EP disclosed
US-9962369-B2 Methods and compositions for transdermal delivery SPRAYABLE HOLDINGS, INC. (US) 2018-05-08 US disclosed
US-9949952-B2 Methods and compositions for transdermal delivery SPRAYABLE HOLDINGS, INC. (US) 2018-04-24 US disclosed
EP-3130615-A1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2017-02-15 EP disclosed
US-20160317435-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS SPRAYABLE HOLDINGS, INC. 2016-11-03 US disclosed
EP-2386579-B1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2016-10-12 EP disclosed
EP-2386580-B1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2016-10-12 EP disclosed
EP-2059539-B1 USE OF A GLYOXYLATED VINYLAMIDE POLYMER AS DRY AND WET STRENGTH AID FOR PAPER BASF SE (DE) 2011-11-16 EP disclosed
EP-2386580-A2 Glyoxalation of vinylamide polymer BASF SE (DE) 2011-11-16 EP disclosed
US-8039031-B2 Tuning the electromagnetic field relating to a sample parameter and monitoring a sample quality; particularly relating to drying of corn with high energy efficiency to produce high quality dried corn, with a low to very low level of cracks. Energy Systems Engineering LLC (US) 2011-10-18 US disclosed
US-20110224374-A1 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2011-09-15 US disclosed
EP-2343324-A1 Glyoxalated poly(n-vinylamine) BASF SE (DE) 2011-07-13 EP disclosed
EP-2215130-A2 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2010-08-11 EP disclosed
EP-2059539-A2 GLYOXALATION OF VINYLAMIDE POLYMER Ciba Holding Inc. (CH) 2009-05-20 EP disclosed
WO-2009059725-A2 GLYOXALATED POLY (N-VINYLAMINE) BASF SE (DE) 2009-05-14 WO disclosed
WO-2008028865-A2 GLYOXALATION OF VINYLAMIDE POLYMER CIBA HOLDING INC. (GB) 2008-03-13 WO disclosed
US-4221617-A HETEROPOLYMERS, ALKYLARYL SULFONATES UNITED TECHNOLOGIES CORPORATION (US) 1980-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160317435-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS TES, CCR7, CES2 ALDH1A1 1876/4885CYP1A2 35/4885SMN1; SMN2 2525/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.