Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.74 |
| ▸ | CTSK | P43235 | 18/20 | 0.74 |
| ▸ | CTSB | P07858 | 17/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL347127 | 0.85 | CTSS (1.00) | CTSSCTSKCTSB | |
| SCHEMBL8224249 | 0.78 | CTSB (0.67) | CTSSCTSKCTSB | |
| SCHEMBL11917586 | 0.76 | CTSS (0.71) | CTSSCTSKCTSB | |
| SCHEMBL8220646 | 0.71 | CTSB (0.74) | CTSSCTSKCTSB | |
| SCHEMBL8225932 | 0.71 | CTSB (0.65) | CTSSCTSKCTSB | |
| SCHEMBL8227148 | 0.70 | CTSB (0.76) | CTSSCTSKCTSB | |
| SCHEMBL8229164 | 0.70 | LMNA (0.42) | CTSSCTSKCTSB | |
| SCHEMBL8218566 | 0.69 | CTSB (0.73) | CTSSCTSKCTSB | |
| SCHEMBL8223762 | 0.69 | CTSB (0.53) | CTSSCTSKCTSB | |
| SCHEMBL8224286 | 0.69 | CTSB (0.55) | CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2520568-A1 | Spirocyclic nitriles as inhibitors of protease | SANOFI (FR) | 2012-11-07 | — | — | EP | disclosed |