Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781860 | 1.00 | DAGLB (0.46) | DAGLBADAM17CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL4725342 | 0.88 | HPGD (0.41) | MEN1KMT2ACYP17A1 | |
| SCHEMBL5230465 | 0.87 | FAAH (0.43) | CYP1A2CYP3A4CYP2C19KDM4EMEN1 | |
| SCHEMBL8224323 | 0.84 | GPR119 (0.51) | DAGLBADAM17CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8222689 | 0.82 | CHRNB4 (0.48) | CYP1A2CYP3A4CYP2C9CYP2C19DPP4 | |
| SCHEMBL3076594 | 0.80 | LMNA (0.44) | DPP4KDM4E | |
| SCHEMBL3076592 | 0.80 | LMNA (0.44) | DPP4KDM4E | |
| SCHEMBL4725326 | 0.80 | OPRD1 (0.38) | DAGLBADAM17MKNK1MKNK2DPP4 | |
| SCHEMBL4776201 | 0.80 | ROCK2 (0.42) | DAGLBADAM17SCD | |
| SCHEMBL4776197 | 0.80 | ROCK2 (0.42) | DAGLBADAM17SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |