O-Xylene

O-Xylene

SCHEMBL822495

Cc1cc(C)cc(C)c1.Cc1ccccc1.Cc1ccccc1C.c1ccccc1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 5/20 0.65
TSHR P16473 3/20 0.65
LMNA P02545 1/20 0.65
ALOX12 P18054 1/20 0.65
CYP1A2 P05177 2/20 0.42
CYP2A6 P11509 1/20 0.42
NPSR1 Q6W5P4 1/20 0.41
CYP2C19 P33261 1/20 0.41
HPGD P15428 1/20 0.40
ALDH1A1 P00352 4/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
TDP1 Q9NUW8 2/20 0.39
FFAR4 Q5NUL3 1/20 0.39
MAPT P10636 1/20 0.38
CYP3A4 P08684 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
M-Xylene SCHEMBL12503828 0.92 ACHE (0.67) ACHETSHRLMNAALOX12CYP1A2
M-Xylene SCHEMBL10914330 0.92 ACHE (0.67) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL1060158 0.91 ACHE (0.71) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL11209551 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL11765114 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL452170 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL8910096 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL11240856 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL10822510 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2
O-Xylene SCHEMBL1088985 0.91 ACHE (0.79) ACHETSHRLMNAALOX12CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110960881-B Control structure and control method of Kaibel bulkhead rectifying tower 中国石油化工股份有限公司 2022-09-27 CN disclosed
CN-110960881-A Control structure and control method of Kaibel bulkhead rectifying tower 中国石油化工股份有限公司 2020-04-07 CN disclosed
US-9017624-B2 Continuous process for converting natural gas to liquid hydrocarbons REACTION 35, LLC (US) 2015-04-28 US disclosed
US-8921625-B2 Continuous process for converting natural gas to liquid hydrocarbons Reaction35, LLC (US) 2014-12-30 US disclosed
US-8449849-B2 Continuous process for converting natural gas to liquid hydrocarbons GRT, INC. (US) 2013-05-28 US disclosed
US-8415517-B2 Continuous process for converting natural gas to liquid hydrocarbons GRT, INC. (US) 2013-04-09 US disclosed
US-20130078157-A1 CONTINUOUS PROCESS FOR CONVERTING NATURAL GAS TO LIQUID HYDROCARBONS REACTION 35, LLC 2013-03-28 US disclosed
US-8273929-B2 Continuous process for converting natural gas to liquid hydrocarbons GRT, INC. (US) 2012-09-25 US disclosed
US-20120215034-A1 PROCESS FOR CONVERTING HYDROCARBON FEEDSTOCKS WITH ELECTROLYTIC AND PHOTOELECTROCATALYTIC RECOVERY OF HALOGENS REACTION 35, LLC 2012-08-23 US disclosed
US-20120009090-A1 CONTINUOUS PROCESS FOR CONVERTING NATURAL GAS TO LIQUID HYDROCARBONS REACTION 35, LLC 2012-01-12 US disclosed
US-8053616-B2 Continuous process for converting natural gas to liquid hydrocarbons GRT, INC. (US) 2011-11-08 US disclosed
WO-2010124041-A1 PROCESS FOR CONVERTING HYDROCARBON FEEDSTOCKS WITH ELECTROLYTIC AND PHOTOELECTROCATALYTIC RECOVERY OF HALOGENS GRT, INC. (US) 2010-10-28 WO disclosed
US-20100270167-A1 PROCESS FOR CONVERTING HYDROCARBON FEEDSTOCKS WITH ELECTROLYTIC AND PHOTOELECTROCATALYTIC RECOVERY OF HALOGENS REACTION 35, LLC 2010-10-28 US disclosed
US-20100099929-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons REACTION 35, LLC 2010-04-22 US disclosed
US-20100096588-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons REACTION 35, LLC 2010-04-22 US disclosed
US-20100099928-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons REACTION 35, LLC 2010-04-22 US disclosed
US-20100099930-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons REACTION 35, LLC 2010-04-22 US disclosed
US-7579510-B2 Continuous process for converting natural gas to liquid hydrocarbons GRT, INC. (US) 2009-08-25 US disclosed
US-20070238909-A1 for converting methane, natural gas, or other hydrocarbon feedstocks into one or more higher hydrocarbons or olefins by continuously cycling through the steps of alkane halogenation, product formation (carbon-carbon coupling), product separation, and regeneration of halogen REACTION 35, LLC 2007-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070238909-A1 for converting methane, natural gas, or other hydrocarbon feedstocks into one or more higher hydrocarbons or olefins by continuously cycling through the steps of alkane halogenation, product formation (carbon-carbon coupling), product separation, and regeneration of halogen HAO2, AHR, SHH ACHE 3462/4885TSHR 1030/4885LMNA 3452/4885
US-20100099929-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons ALK, GLI2, KDR ACHE 4648/4885TSHR 1722/4885LMNA 2191/4885
US-20100096588-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons DECR1, DECR2, GLI2 ACHE 3862/4885TSHR 1858/4885LMNA 1914/4885
US-20100099928-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons ALK, HRAS, GLI2 ACHE 4632/4885TSHR 2357/4885LMNA 2011/4885
US-20100099930-A1 Continuous Process for Converting Natural Gas to Liquid Hydrocarbons HAO2, SHH, AHR ACHE 2900/4885TSHR 1568/4885LMNA 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.