Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21198466 | 0.83 | LMNA (0.46) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL8225934 | 0.83 | LMNA (0.46) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4963357 | 0.82 | CYP2D6 (0.39) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4959882 | 0.82 | ALDH1A1 (0.39) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL4443279 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2D6TSHRMAPK1 | |
| SCHEMBL4225253 | 0.78 | ALDH1A1 (0.43) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL12134880 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2D6TSHRMAPK1 | |
| SCHEMBL14046970 | 0.78 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2D6TSHRMAPK1 | |
| SCHEMBL4224280 | 0.78 | ALDH1A1 (0.41) | CA2ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL3208378 | 0.75 | CYP2D6 (0.45) | ALDH1A1CYP3A4CYP2D6TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | HTR2C, HTR1D, HTR1A | CA2 4153/4885ALDH1A1 814/4885CYP3A4 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.