Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151368 | 0.82 | HSD11B1 (0.45) | HSD11B1SMN1; SMN2OPRM1HDAC4ALDH1A1 | |
| SCHEMBL8142155 | 0.79 | ALDH1A1 (0.42) | HSD11B1SMN1; SMN2OPRM1HDAC4ALDH1A1 | |
| SCHEMBL4435171 | 0.72 | AKR1C1 (0.52) | AKR1C1HSD11B1HTTSMN1; SMN2OPRM1 | |
| SCHEMBL15504851 | 0.71 | TDP1 (0.60) | HTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL15514419 | 0.71 | TDP1 (0.60) | HTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL876037 | 0.70 | AKR1C1 (0.44) | AKR1C1HSD11B1HDAC4SLC22A1 | |
| SCHEMBL838361 | 0.70 | AKR1C1 (0.44) | AKR1C1HSD11B1HDAC4SLC22A1 | |
| SCHEMBL2722547 | 0.69 | AKR1C1 (0.57) | AKR1C1HSD11B1HTTSMN1; SMN2OPRM1 | |
| SCHEMBL501923 | 0.69 | AKR1C1 (0.57) | AKR1C1HSD11B1HTTSMN1; SMN2OPRM1 | |
| SCHEMBL12328538 | 0.69 | ALDH1A1 (0.48) | HTTSMN1; SMN2XDHALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008050200-A1 | OXADIAZOLE COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-05-02 | — | — | WO | disclosed |