Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 5/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822694 | 0.78 | MAPT (0.57) | KDM4EMAOAHTR2A | |
| Phenanthridine SCHEMBL30823553 | 0.74 | GPR3 (1.00) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL30914262 | 0.74 | GPR3 (1.00) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL8666 | 0.74 | GPR3 (1.00) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL9106884 | 0.74 | GPR3 (1.00) | GPR3KDM4EADORA3TOP2APDPK1 | |
| SCHEMBL9395199 | 0.74 | ADORA3 (0.55) | GPR3KDM4EADORA3TLR7TOP2A | |
| Phenanthridine SCHEMBL29087045 | 0.74 | GPR3 (0.87) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL23003530 | 0.73 | GPR3 (0.95) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL8505090 | 0.73 | GPR3 (0.95) | GPR3KDM4EADORA3TOP2APDPK1 | |
| Phenanthridine SCHEMBL460289 | 0.73 | GPR3 (0.95) | GPR3KDM4EADORA3TOP2APDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120007063-A1 | USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS | DDT, DBF4, POU5F1 | GPR3 3124/4885KDM4E 1835/4885ADORA3 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.