SCHEMBL822698

SCHEMBL822698

Cn1c(-c2ccccc2)nnc1-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 9/20 0.68
TSHR P16473 1/20 0.61
KMT2A Q03164 1/20 0.58
DRD2 P14416 1/20 0.56
AVPR1A P37288 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
NR1H2 P55055 1/20 0.48
NR1H3 Q13133 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL889637 0.88 HSD11B1 (0.56) HSD11B1TSHRKMT2ADRD2AVPR1A
SCHEMBL15206947 0.85 HSD11B1 (0.69) HSD11B1TSHRKMT2ADRD2L3MBTL1
SCHEMBL13872765 0.84 KMT2A (0.54) HSD11B1TSHRKMT2ADRD2AVPR1A
SCHEMBL392717 0.84 HSD11B1 (0.53) HSD11B1TSHRKMT2ADRD2AVPR1A
SCHEMBL7454054 0.84 HSD11B1 (0.53) HSD11B1TSHRKMT2ADRD2AVPR1A
Potassium Ion SCHEMBL4705992 0.83 HSD11B1 (0.51) HSD11B1TSHRKMT2ADRD2AVPR1A
SCHEMBL12383282 0.82 NPC1 (0.55) HSD11B1TSHRL3MBTL1ALDH1A1NPC1
SCHEMBL11525112 0.82 NPC1 (0.54) HSD11B1ALDH1A1NPC1RAB9A
SCHEMBL13589292 0.82 HSD11B1 (0.53) HSD11B1TSHRKMT2ADRD2AVPR1A
SCHEMBL14425750 0.81 HSD11B1 (0.50) HSD11B1TSHRKMT2ADRD2AVPR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11063220-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2021-07-13 US disclosed
WO-2020194409-A1 LIGHT EMITTING DEVICE シャープ株式会社 2020-10-01 WO disclosed
EP-2590967-B1 USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS UDC IRELAND LTD (IE) 2019-05-15 EP disclosed
US-9960365-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-9520566-B2 Condensed cyclic compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-12-13 US disclosed
WO-2016171358-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE 삼성에스디아이 주식회사 2016-10-27 WO disclosed
US-9159928-B2 Amine-oxide-group-containing conjugated polymer photoelectric material and use thereof SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2015-10-13 US disclosed
US-9067919-B2 Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics BASF SE (DE) 2015-06-30 US disclosed
US-20150038602-A1 AMINE-OXIDE-GROUP-CONTAINING CONJUGATED POLYMER PHOTOELECTRIC MATERIAL AND USE THEREOF SOUTH CHINA UNIVERSITY OF TECHNOLOGY (CN) 2015-02-05 US disclosed
WO-2012121936-A2 PYRIDYL CARBENE PHOSPHORESCENT EMITTERS UNIVERSAL DISPLAY CORPORATION (US) 2012-09-13 WO disclosed
WO-2012023947-A1 BICARBAZOLE COMPOUNDS FOR OLEDS UNIVERSAL DISPLAY CORPORATION (US) 2012-02-23 WO disclosed
US-20120007063-A1 USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS BASF SE (DE) 2012-01-12 US disclosed
US-4164480-A POLYMER STABILIZERS EASTMAN KODAK COMPANY (US) 1979-08-14 US disclosed
US-4105631-A MULTICHROMOPHORIC ULTRAVIOLET STABILIZERS AND THEIR USE IN ORGANIC COMPOSITIONS EASTMAN KODAK COMPANY (US) 1978-08-08 US disclosed
US-4043973-A PIGMENTS, COLORANTS, FILLERS, REINFORCING AGENTS EASTMAN KODAK COMPANY (US) 1977-08-23 US disclosed
US-3939115-A OXADIAZOLES EASTMAN KODAK COMPANY (US) 1976-02-17 US disclosed
US-3936419-A Multichromophoric ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007063-A1 USE OF DIBENZOFURANS AND DIBENZOTHIOPHENES SUBSTITUTED BY NITROGEN-BONDED FIVE-MEMBERED HETEROCYCLIC RINGS IN ORGANIC ELECTRONICS DDT, DBF4, POU5F1 HSD11B1 3301/4885TSHR 2801/4885KMT2A 2436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.