Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10163556 | 0.92 | L3MBTL1 (0.38) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL10208198 | 0.91 | ALDH1A1 (0.38) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL10208196 | 0.90 | MMP13 (0.38) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL8228662 | 0.90 | MMP13 (0.39) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL8225958 | 0.90 | TP53 (0.44) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL8226231 | 0.89 | MMP13 (0.40) | ADAMTS4MMP3MMP13TP53LMNA | |
| SCHEMBL8229567 | 0.88 | ROCK2 (0.42) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL8229036 | 0.88 | KMT2A (0.40) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL10208197 | 0.86 | TP53 (0.39) | ADAMTS4MMP3MMP8MMP12MMP13 | |
| SCHEMBL10162851 | 0.86 | MAPT (0.47) | ADAMTS4MMP3MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007139856-A2 | HETEROBICYCLIC METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS, INC. (US) | 2007-12-06 | — | — | WO | disclosed |