Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5345839 | 0.77 | MAPT (0.61) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL8034913 | 0.76 | TLR8 (0.56) | ALDH1A1KDM4EHSD17B10HPGDMAPT | |
| SCHEMBL8235818 | 0.74 | MAPT (0.54) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL24461941 | 0.73 | MAPT (0.49) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL5319270 | 0.72 | MAPT (0.47) | ALDH1A1KDM4EKMT2AHSD17B10MEN1 | |
| SCHEMBL25383681 | 0.72 | MAPT (0.47) | ALDH1A1KDM4EKMT2AMAPK1MEN1 | |
| SCHEMBL8235194 | 0.71 | MAPT (0.49) | ALDH1A1KDM4EKMT2AMEN1HPGD | |
| SCHEMBL5320946 | 0.70 | ALDH1A1 (0.51) | ALDH1A1KDM4EKMT2AMEN1L3MBTL1 | |
| SCHEMBL5347074 | 0.69 | MAPT (0.50) | ALDH1A1KDM4EKMT2AHTTMAPT | |
| SCHEMBL4750651 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |