Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27648726 | 0.90 | PKM (0.46) | NOTUMPKMMGLLALDH1A1MAPT | |
| SCHEMBL9272142 | 0.77 | MEN1 (0.42) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8470236 | 0.77 | PDPK1 (0.35) | — | |
| SCHEMBL2211763 | 0.74 | KDM4E (0.46) | NOTUMPKMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19106909 | 0.73 | RXRA (0.41) | NOTUMALDH1A1MAPTSMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL5189603 | 0.73 | KDM4E (0.44) | NOTUMPKMALDH1A1MAPTSMN1; SMN2 | |
| Bromide SCHEMBL28126767 | 0.73 | KDM4E (0.44) | NOTUMPKMALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27648801 | 0.72 | NOTUM (0.46) | NOTUMPKMMGLLALDH1A1MAPT | |
| SCHEMBL27704435 | 0.72 | PKM (0.44) | NOTUMPKMMGLLALDH1A1MAPT | |
| SCHEMBL3228579 | 0.71 | KDM4E (0.59) | NOTUMPKMMGLLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | claimed |
| WO-2007130821-A2 | MGLUR5 MODULATORS II | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | disclosed |
| EP-0611232-A1 | Process for the preparation of phenylbenzamide derivatives | RHONE-POULENC AGROCHIMIE (FR) | 1994-08-17 | — | — | EP | disclosed |