Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3023510 | 0.80 | ADRA2A (0.44) | CYP2C19MAOAMAOBKDM4ECYP2D6 | |
| SCHEMBL17815212 | 0.78 | CYP2C19 (0.39) | CYP2C19MAOAMAOBKDM4ECYP2D6 | |
| SCHEMBL14402455 | 0.77 | PNMT (0.43) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4825313 | 0.77 | SLC6A2 (0.42) | CYP2C19MAOAMAOBKDM4ECYP2D6 | |
| SCHEMBL19705567 | 0.76 | CYP2C19 (0.38) | CYP2C19MAOAMAOBKDM4ECYP2D6 | |
| SCHEMBL8184550 | 0.76 | CYP2C19 (0.38) | CYP2C19MAOAMAOBKDM4ECYP2D6 | |
| SCHEMBL13875038 | 0.75 | MAOA (0.44) | MAOAMAOBKDM4ECYP2D6ADRA1A | |
| SCHEMBL17197369 | 0.74 | DRD1 (0.45) | MAOAMAOBDRD1DRD3DRD2 | |
| Hydrochloric Acid SCHEMBL6613546 | 0.74 | ALDH1A1 (0.42) | MAOAMAOBKDM4ECYP2D6CYP1A2 | |
| SCHEMBL6608100 | 0.73 | HRH4 (0.39) | KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115408-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-10-18 | — | — | WO | disclosed |