Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SELP | P16109 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905948 | 0.84 | FAAH (0.68) | FAAHDGKAKMT2AKDM4EDUSP3 | |
| SCHEMBL9905949 | 0.82 | FAAH (0.82) | FAAHDGKAKMT2AKDM4EDUSP3 | |
| SCHEMBL15451530 | 0.82 | FAAH (0.82) | FAAHDGKAKMT2AKDM4EDUSP3 | |
| SCHEMBL6894863 | 0.81 | ADORA3 (0.47) | FAAHKMT2AKDM4EMEN1LMNA | |
| SCHEMBL16675431 | 0.81 | ADORA3 (0.47) | FAAHKMT2AKDM4EMEN1LMNA | |
| SCHEMBL12415431 | 0.81 | ADORA3 (0.47) | FAAHKMT2AKDM4EMEN1LMNA | |
| SCHEMBL6348381 | 0.81 | LPAR1 (0.53) | FAAH | |
| SCHEMBL29376090 | 0.81 | FAAH (0.80) | FAAHDGKAKMT2AKDM4EDUSP3 | |
| 1-Monolinolenin SCHEMBL23611226 | 0.80 | FAAH (0.78) | FAAHDGKAKMT2AKDM4EDUSP3 | |
| SCHEMBL13623309 | 0.80 | FAAH (0.78) | FAAHDGKAKMT2AKDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308955-B1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2017-02-22 | — | — | EP | disclosed |
| US-8877952-B2 | Pre-esterification of primary polyols to improve solubility in solvents used in the polyol process | BATTELLE MEMORIAL INSTITUTE (US) | 2014-11-04 | — | — | US | disclosed |
| US-8871960-B2 | Preparation of esters and polyols by initial oxidative cleavage of fatty acids followed by esterification reactions | BATTELLE MEMORIAL INSTITUTE (US) | 2014-10-28 | — | — | US | disclosed |
| US-8859794-B2 | Use of fatty acids as feed material in polyol process | BATTELLE MEMORIAL INSTITUTE (US) | 2014-10-14 | — | — | US | disclosed |
| US-8624047-B2 | Solvent-less preparation of polyols by ozonolysis | BATTELLE MEMORIAL INSTITUTE (US) | 2014-01-07 | — | — | US | disclosed |
| US-8178703-B2 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2012-05-15 | — | — | US | disclosed |
| US-20110269982-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269981-A1 | Pre-Esterification Of Primary Polyols To Improve Solubility In Solvents Used In The Polyol Process | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269979-A1 | Preparation of Esters and Polyols by Initial Oxidative Cleavage of Fatty Acids Followed by Esterification Reactions | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110269978-A1 | Solvent-less Preparation of Polyols by Ozonolysis | BATTELLE MEMORIAL INSTITUTE (US) | 2011-11-03 | — | — | US | disclosed |
| US-20110237812-A1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | BATTELLE MEMORIAL INSTITUTE (US) | 2011-09-29 | — | — | US | disclosed |
| US-7994354-B2 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2011-08-09 | — | — | US | disclosed |
| EP-2308955-A1 | Methods for production of polyols from oils and their use in the production of polyesters and polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2011-04-13 | — | — | EP | disclosed |
| US-20090216040-A1 | Methods For Production Of Polyols From Oils And Their Use In the Production of Polyesters and Polyurethanes | BATTELLE MEMORIAL INSTITUTE (US) | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269979-A1 | Preparation of Esters and Polyols by Initial Oxidative Cleavage of Fatty Acids Followed by Esterification Reactions | FASN, ELOVL1, ACSL1 | FAAH 61/4885DGKA 181/4885KMT2A 2762/4885 |
| US-20110269978-A1 | Solvent-less Preparation of Polyols by Ozonolysis | MGLL, PUF60, DAGLA | FAAH 107/4885DGKA 94/4885KMT2A 1500/4885 |
| US-20110269982-A1 | USE OF FATTY ACIDS AS FEED MATERIAL IN POLYOL PROCESS | FASN, ACSL1, ELOVL1 | FAAH 50/4885DGKA 176/4885KMT2A 1597/4885 |
| US-20090216040-A1 | Methods For Production Of Polyols From Oils And Their Use In the Production of Polyesters and Polyurethanes | FASN, MGLL, PUF60 | FAAH 103/4885DGKA 92/4885KMT2A 2232/4885 |
| US-20110237812-A1 | METHODS FOR PRODUCTION OF POLYOLS FROM OILS AND THEIR USE IN THE PRODUCTION OF POLYESTERS AND POLYURETHANES | FASN, MGLL, PUF60 | FAAH 103/4885DGKA 92/4885KMT2A 2232/4885 |
| US-20110269981-A1 | Pre-Esterification Of Primary Polyols To Improve Solubility In Solvents Used In The Polyol Process | MGLL, FASN, ELOVL1 | FAAH 179/4885DGKA 261/4885KMT2A 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.