Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334247 | 0.83 | ALDH1A1 (0.51) | ALDH1A1GRM2POLBMMP1MMP2 | |
| SCHEMBL14037658 | 0.78 | CYP19A1 (0.47) | LMNAGRM2CYP19A1 | |
| SCHEMBL17622983 | 0.76 | HTT (0.57) | ALDH1A1POLBMAPT | |
| SCHEMBL24126788 | 0.73 | ELANE (0.56) | GRM2 | |
| SCHEMBL31567037 | 0.72 | OPRD1 (0.39) | ALDH1A1GRM2 | |
| SCHEMBL8293499 | 0.72 | CYP19A1 (0.41) | ALDH1A1GRM2POLBMMP1MMP2 | |
| SCHEMBL19093590 | 0.71 | OPRM1 (0.65) | OPRM1OPRL1 | |
| SCHEMBL19093588 | 0.71 | OPRM1 (0.65) | OPRM1OPRL1 | |
| SCHEMBL19104843 | 0.71 | OPRM1 (0.65) | OPRM1OPRL1 | |
| SCHEMBL14359249 | 0.69 | CYP19A1 (0.42) | GRM2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |