Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037658 | 0.83 | CYP19A1 (0.47) | GRM2CYP19A1 | |
| SCHEMBL8233154 | 0.83 | LMNA (0.41) | ALDH1A1MMP1MMP2MMP9GRM2 | |
| SCHEMBL24126788 | 0.80 | ELANE (0.56) | KMT2AGRM2PTGDR2 | |
| SCHEMBL8293499 | 0.79 | CYP19A1 (0.41) | ALDH1A1KMT2AATMMMP1MMP2 | |
| SCHEMBL14359249 | 0.77 | CYP19A1 (0.42) | GRM2CYP19A1 | |
| SCHEMBL14359304 | 0.75 | HTR1A (0.44) | KMT2APOLBCYP19A1 | |
| SCHEMBL22728348 | 0.75 | KMT2A (0.50) | ALDH1A1KMT2AATMCA12CA9 | |
| Methsuximide SCHEMBL34852 | 0.74 | CYP19A1 (0.70) | ALDH1A1KMT2AMMP1MMP2MMP9 | |
| Methsuximide SCHEMBL34853 | 0.74 | CYP19A1 (0.70) | ALDH1A1KMT2AMMP1MMP2MMP9 | |
| Morsuximide SCHEMBL357911 | 0.73 | ALDH1A1 (0.45) | ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |