Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 9/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8237709 | 0.96 | MAPT (0.41) | SMN1; SMN2MAPTCXCR3TP53 | |
| SCHEMBL8236364 | 0.94 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTCXCR3 | |
| SCHEMBL8236040 | 0.91 | MAPT (0.47) | MAPTCXCR3TP53 | |
| SCHEMBL8228005 | 0.88 | TSHR (0.44) | SMN1; SMN2MAPTCXCR3 | |
| SCHEMBL8236412 | 0.86 | SLC6A9 (0.39) | SMN1; SMN2MAPTCXCR3SLC6A9 | |
| SCHEMBL8234249 | 0.85 | PSMB5 (0.47) | CXCR3 | |
| SCHEMBL8236031 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTCXCR3TP53 | |
| SCHEMBL8236758 | 0.85 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPTCXCR3TP53 | |
| SCHEMBL8233464 | 0.84 | CXCR3 (0.41) | SMN1; SMN2MAPTCXCR3SLC6A9TP53 | |
| SCHEMBL8228222 | 0.84 | CXCR3 (0.46) | SMN1; SMN2MAPTCXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |