Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8234155 | 0.96 | SMN1; SMN2 (0.47) | MAPTSMN1; SMN2CXCR3TP53 | |
| SCHEMBL8236412 | 0.90 | SLC6A9 (0.39) | MAPTSMN1; SMN2PSMB5CXCR3KMT2A | |
| SCHEMBL8236040 | 0.89 | MAPT (0.47) | MAPTCXCR3TP53 | |
| SCHEMBL8236364 | 0.89 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2CXCR3KMT2AMEN1 | |
| SCHEMBL8234240 | 0.86 | KMT2A (0.43) | MAPTSMN1; SMN2PSMB5CXCR3KMT2A | |
| SCHEMBL8228005 | 0.82 | TSHR (0.44) | MAPTSMN1; SMN2CXCR3KMT2AMEN1 | |
| SCHEMBL8234249 | 0.81 | PSMB5 (0.47) | PSMB5CXCR3 | |
| SCHEMBL8236031 | 0.81 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2CXCR3TP53THRB | |
| SCHEMBL8236758 | 0.80 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2CXCR3TP53THRB | |
| SCHEMBL8233464 | 0.80 | CXCR3 (0.41) | MAPTSMN1; SMN2PSMB5CXCR3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082666-A1 | ACYLAMINOIMIDAZOLES | BAYER HEALTHCARE AG (DE) | 2007-07-26 | — | — | WO | disclosed |