Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5030644 | 0.82 | SCN5A (0.50) | ALDH1A1MAPK14LMNASCN5ACYP1A2 | |
| SCHEMBL27417295 | 0.75 | ALDH1A1 (0.47) | ALDH1A1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL30800856 | 0.71 | MAPT (0.46) | ALDH1A1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL19035328 | 0.70 | ALDH1A1 (0.41) | ALDH1A1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL24328007 | 0.70 | ALDH1A1 (0.49) | ALDH1A1ABL1PLK1 | |
| SCHEMBL5030834 | 0.69 | RAB9A (0.40) | ALDH1A1LMNACYP1A2MAPK1KDM4E | |
| SCHEMBL8233425 | 0.69 | RARB (0.46) | ALDH1A1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL181559 | 0.69 | MAPT (0.52) | ALDH1A1LMNASCN5ACYP1A2MAOA | |
| SCHEMBL11798071 | 0.69 | ALDH1A1 (0.54) | ALDH1A1CYP1A2HDAC1HDAC8HDAC6 | |
| SCHEMBL10997394 | 0.69 | LMNA (0.56) | LMNASCN5ACYP1A2MAOACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007087442-A2 | SUBSTITUTED BIARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2007-08-02 | — | — | WO | disclosed |