Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13940202 | 0.85 | GAA (0.55) | PKMHTTPOLBNPC1RAB9A | |
| SCHEMBL29277557 | 0.84 | AGTR1 (0.49) | PKMHTTPOLBLMNASMN1; SMN2 | |
| SCHEMBL29277549 | 0.81 | HTR2A (0.51) | PKMHTTPOLBNPC1LMNA | |
| SCHEMBL29277556 | 0.81 | HTT (0.59) | PKMHTTPOLBLMNASMN1; SMN2 | |
| SCHEMBL13939998 | 0.80 | TSHR (0.47) | PKMHTTPOLBNPC1RAB9A | |
| SCHEMBL7274163 | 0.76 | PKM (0.63) | PKMHTTPOLBTDP1LMNA | |
| SCHEMBL28270265 | 0.76 | PKM (0.68) | PKMHTTPOLBNPC1RAB9A | |
| SCHEMBL29277552 | 0.73 | CYP11B1 (0.47) | PKMHTTRAB9ATDP1SMN1; SMN2 | |
| SCHEMBL2900381 | 0.73 | PKM (0.83) | PKMHTTPOLBSMN1; SMN2GAA | |
| SCHEMBL30375768 | 0.72 | PKM (0.46) | PKMHTTPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007103683-A2 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PRODUCTION | ROSKAMP RESEARCH LLC (US) | 2007-09-13 | — | — | WO | disclosed |