Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.55 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | CTSE | P14091 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8232404 | 0.82 | BDKRB2 (0.44) | REN | |
| SCHEMBL8232425 | 0.81 | REN (0.52) | RENCTSDCTSE | |
| SCHEMBL8241741 | 0.81 | REN (0.51) | REN | |
| SCHEMBL9725818 | 0.80 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL9739264 | 0.80 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL9725812 | 0.80 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL9725825 | 0.80 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL9749328 | 0.78 | REN (0.53) | RENCTSDCTSE | |
| SCHEMBL10768958 | 0.77 | REN (0.51) | REN | |
| SCHEMBL9513094 | 0.77 | REN (0.62) | RENCTSDCTSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238774-B2 | Statine derivatives for the treatment of Alzheimer's disease III | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-03 | — | — | US | disclosed |
| US-7238774-B2 | Statine derivatives for the treatment of Alzheimer's disease III | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-07-03 | — | — | US | disclosed |
| US-20060100158-A1 | Statine derivatives for the treatment of Alzheimer's disease III | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | US | disclosed |
| US-20060100158-A1 | Statine derivatives for the treatment of Alzheimer's disease III | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100158-A1 | Statine derivatives for the treatment of Alzheimer's disease III | HMGCR, LDLR, PCSK9 | REN 694/4885CTSD 2529/4885CTSE 2097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.