SCHEMBL823959

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL824002	0.85	ALDH1A1 (0.47)	LSSCYP19A1MAPTALDH1A1KMT2A
	SCHEMBL13355561	0.84	ALDH1A1 (0.42)	LSSCYP19A1MAPTALDH1A1KMT2A
	SCHEMBL1097194	0.79	KMT2A (0.40)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL1096798	0.76	TSHR (0.46)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL9220403	0.74	MAPT (0.52)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL985801	0.72	MAPT (0.61)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL2086989	0.72	MAPT (0.61)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL29897293	0.72	MAPT (0.61)	CYP19A1MAPTALDH1A1KMT2AHPGD
	SCHEMBL824063	0.72	MAPT (0.52)	MAPTALDH1A1KMT2AHPGDRAB9A
	SCHEMBL29336516	0.71	PYCR1 (0.59)	LSSALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.