Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGF1 | P05230 | 1/20 | 0.51 |
| ▸ | FGF2 | P09038 | 1/20 | 0.51 |
| ▸ | VEGFA | P15692 | 1/20 | 0.51 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.51 |
| ▸ | MDK | P21741 | 4/20 | 0.50 |
| ▸ | HLCS | P50747 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8239553 | 1.00 | FGF1 (0.51) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL9898615 | 0.77 | MDK (0.65) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL9898618 | 0.77 | MDK (0.65) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL9898612 | 0.77 | MDK (0.65) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL2359254 | 0.75 | HLCS (0.65) | HLCSPKMF2PRSS1PRSS2 | |
| SCHEMBL2359251 | 0.74 | HLCS (0.56) | HLCSPKMF2PRSS1PRSS2 | |
| SCHEMBL16264872 | 0.71 | MDK (0.75) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL18653674 | 0.71 | MDK (0.75) | FGF1FGF2VEGFAHPSEMDK | |
| SCHEMBL4965567 | 0.67 | HLCS (0.57) | HPSEHLCSPKMF2PRSS1 | |
| SCHEMBL19409062 | 0.67 | TDP1 (0.56) | HLCSPKMF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011019419-A1 | CARBOHYDRATE-MEDIATED TUMOR TARGETING | ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2011-02-17 | — | — | WO | claimed |