Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.52 |
| ▸ | RARB | P10826 | 1/20 | 0.52 |
| ▸ | RARG | P13631 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | CDC7 | O00311 | 2/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8238620 | 0.87 | RARA (0.54) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL8239693 | 0.86 | RARA (0.53) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL9975604 | 0.84 | RARA (0.51) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL7220981 | 0.78 | RAB9A (0.67) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL9975608 | 0.78 | TRPM8 (0.46) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL9975603 | 0.77 | SMN1; SMN2 (0.47) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL9975605 | 0.76 | MAPT (0.48) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL8241893 | 0.76 | MAPT (0.45) | RARARARBRARGMAPTRAB9A | |
| SCHEMBL13934090 | 0.75 | CA1 (0.59) | MAPTRAB9ASMN1; SMN2NPC1TSHR | |
| SCHEMBL491414 | 0.74 | MEN1 (0.64) | RARARARBRARGMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394798-B2 | Compositions and methods for inducing neuronal differentiation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2013-03-12 | — | — | US | disclosed |
| US-20120157457-A1 | COMPOSITIONS AND METHODS FOR INDUCING NEURONAL DIFFERENTIATION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120157457-A1 | COMPOSITIONS AND METHODS FOR INDUCING NEURONAL DIFFERENTIATION | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2012-06-21 | — | — | US | disclosed |
| US-8105581-B2 | Compositions and methods for inducing neuronal differentiation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-01-31 | — | — | US | disclosed |
| US-20100166710-A1 | Compositions and Methods for Inducing Neuronal Differentiation | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-07-01 | — | — | US | disclosed |
| WO-2007064891-A1 | COMPOSITIONS AND METHODS FOR INDUCING NEURONAL DIFFERENTIATION | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100166710-A1 | Compositions and Methods for Inducing Neuronal Differentiation | CHAT, DCX, GAP43 | RARA 163/4885RARB 77/4885RARG 134/4885 |
| US-20120157457-A1 | COMPOSITIONS AND METHODS FOR INDUCING NEURONAL DIFFERENTIATION | CHAT, DCX, GAP43 | RARA 163/4885RARB 77/4885RARG 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.