SCHEMBL824010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14530985	0.86	ALDH1A1 (0.39)	KMODYRK1ACLK4ALDH1A1MEN1
	SCHEMBL823895	0.81	KMO (0.41)	KMODYRK1ACLK4ALDH1A1MEN1
	SCHEMBL823894	0.78	KMO (0.50)	KMODYRK1ACLK4MEN1KMT2A
	SCHEMBL3045105	0.77	CDK5 (0.58)	MEN1KMT2AJAK2EGFRCDK2
	SCHEMBL12408680	0.75	MEN1 (0.61)	KMODYRK1ACLK4ALDH1A1MEN1
	SCHEMBL3045102	0.74	JAK2 (0.49)	JAK2EGFRPIK3CAPIK3CBPIK3CG
	SCHEMBL17744653	0.73	KMO (0.51)	KMODYRK1ACLK4ALDH1A1MEN1
	SCHEMBL823934	0.72	ABL1 (0.47)	JAK2EGFRPIK3CAPIK3CBPIK3CG
	SCHEMBL12801634	0.72	KMO (0.50)	KMODYRK1ACLK4ALDH1A1MEN1
	SCHEMBL31391067	0.72	ALDH1A1 (0.52)	KMODYRK1ACLK4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.