Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | CAMKK2 | Q96RR4 | 4/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 3/20 | 0.47 |
| ▸ | BCR | P11274 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | PRKCA | P17252 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045105 | 0.88 | CDK5 (0.58) | JAK2FLT3PIK3CGABL1BCR | |
| SCHEMBL823934 | 0.85 | ABL1 (0.47) | JAK2FLT3PIK3CGMAPK8ABL1 | |
| SCHEMBL4903189 | 0.83 | PIK3CG (0.61) | JAK2FLT3CAMKK2PIK3CGMAPK8 | |
| SCHEMBL12276138 | 0.79 | SYK (0.61) | JAK2FLT3CAMKK2PIK3CGMAPK8 | |
| SCHEMBL27115956 | 0.76 | ABL1 (0.60) | CAMKK2PIK3CGMAPK8GSK3BABL1 | |
| SCHEMBL2939791 | 0.75 | PIK3CG (0.68) | CAMKK2PIK3CGMAPK8GSK3BABL1 | |
| SCHEMBL824010 | 0.74 | KMO (0.41) | JAK2PIK3CGPIK3CAPIK3CBEGFR | |
| SCHEMBL824003 | 0.73 | ABL1 (0.42) | JAK2FLT3PIK3CGABL1BCR | |
| SCHEMBL14254081 | 0.73 | CAMKK2 (0.55) | JAK2CAMKK2PIK3CGMAPK8GSK3B | |
| SCHEMBL14530985 | 0.73 | ALDH1A1 (0.39) | JAK2FLT3EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051221-A1 | SYSTEM FOR PRODUCING BIOCHAR AND METHOD FOR PRODUCING BIOCHAR | KF CO., LTD. (KR) | 2017-02-23 | — | — | US | disclosed |
| US-9133214-B2 | Heteroalkyl linked pyrimidine derivatives | S*BIO PTE LTD (SG) | 2015-09-15 | — | — | US | disclosed |
| EP-2396508-B1 | METHOD FOR CONVERTING HYDRATES BURIED IN THE WATERBOTTOM INTO A MARKETABLE HYDROCARBON COMPOSITION | SHELL INT RESEARCH (NL) | 2013-05-29 | — | — | EP | disclosed |
| US-20120142680-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD. (SG) | 2012-06-07 | — | — | US | disclosed |
| EP-2226466-A1 | Method for producing a marketable hydrocarbon composition from a hydrate deposit buried in the waterbottom | Shell Internationale Research Maatschappij B.V. (NL) | 2010-09-08 | — | — | EP | disclosed |
| EP-1951730-B1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S BIO PTE LTD (SG) | 2010-05-26 | — | — | EP | disclosed |
| US-20090258886-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD. (SG) | 2009-10-15 | — | — | US | disclosed |
| EP-1951730-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*Bio Pte Ltd (SG) | 2008-08-06 | — | — | EP | disclosed |
| WO-2007058628-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | S*BIO PTE LTD (SG) | 2007-05-24 | — | — | WO | disclosed |
| US-6428399-B1 | Polishing apparatus for polishing a hard material-coated wafer | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 2002-08-06 | — | — | US | disclosed |
| US-6307731-B1 | OXYGEN INCLUSION LAYER CONTAINING PRECIOUS AND TRANSITION METALS; ETCHING, ANNEALING, MICROFABRICATION | SONY CORPORATION (JP) | 2001-10-23 | — | — | US | disclosed |
| EP-0530021-A2 | Diamond film and method of producing same | SUMITOMO ELECTRIC INDUSTRIES, LIMITED (JP) | 1993-03-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258886-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | TK1, TK2, DPYD | JAK2 692/4885FLT3 424/4885CAMKK2 1242/4885 |
| US-20120142680-A1 | HETEROALKYL LINKED PYRIMIDINE DERIVATIVES | TK1, TK2, DPYD | JAK2 692/4885FLT3 424/4885CAMKK2 1242/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.