Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | PRKAA2 | P54646 | 5/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.37 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.37 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.37 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242547 | 0.91 | CTSL (0.51) | CTSLCTSSCTSKCTSBCHRM4 | |
| SCHEMBL5590923 | 0.91 | CTSL (0.60) | CTSLCTSSCTSKCTSBCHRM4 | |
| SCHEMBL8245361 | 0.87 | CTSS (0.58) | CTSLCTSSCTSKCTSBCHRM4 | |
| Trifluoroacetic Acid SCHEMBL5591438 | 0.87 | CTSL (0.56) | CTSLCTSSCTSKCTSBCHRM4 | |
| SCHEMBL8242954 | 0.87 | CTSS (0.55) | CTSLCTSSCTSKCTSBPRKAA2 | |
| SCHEMBL8242962 | 0.86 | CTSS (0.55) | CTSLCTSSCTSKCTSBPRKAA2 | |
| SCHEMBL5591422 | 0.84 | CTSL (0.62) | CTSLCTSSCTSKCTSBCHRM4 | |
| SCHEMBL5591580 | 0.82 | CTSS (0.65) | CTSLCTSSCTSKCTSBPRKAA2 | |
| SCHEMBL5591383 | 0.82 | CTSL (0.63) | CTSLCTSSCTSKCTSBCHRM4 | |
| Trifluoroacetic Acid SCHEMBL5591207 | 0.81 | CTSL (0.57) | CTSLCTSSCTSKCTSBCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025774-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |