Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.56 |
| ▸ | CTSL | P07711 | 7/20 | 0.56 |
| ▸ | CTSS | P25774 | 7/20 | 0.56 |
| ▸ | CTSB | P07858 | 2/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8241787 | 0.90 | CTSK (0.69) | CTSKCTSLCTSSCTSBHDAC8 | |
| SCHEMBL8236640 | 0.84 | CTSL (0.57) | CTSKCTSLCTSSCTSBDRD4 | |
| SCHEMBL8270735 | 0.84 | CTSK (0.43) | CTSKCTSLCTSSCTSBCTSD | |
| SCHEMBL8200798 | 0.84 | CTSK (0.79) | CTSKCTSLCTSSCTSBHDAC3 | |
| SCHEMBL3180749 | 0.83 | CTSS (0.50) | CTSKCTSLCTSSCTSBCTSD | |
| SCHEMBL8245909 | 0.82 | CTSL (0.52) | CTSKCTSLCTSSCTSB | |
| SCHEMBL8243959 | 0.82 | CTSK (0.51) | CTSKCTSLCTSSCTSBHDAC3 | |
| SCHEMBL8238286 | 0.82 | CTSL (0.54) | CTSKCTSLCTSSCTSBHDAC3 | |
| SCHEMBL8247857 | 0.81 | CTSK (0.57) | CTSKCTSLCTSSCTSBDRD4 | |
| SCHEMBL8236641 | 0.81 | CTSL (0.66) | CTSKCTSLCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |