Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 5/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8245748 | 0.91 | CTSL (0.51) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL8270007 | 0.89 | CTSL (0.42) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL8245913 | 0.87 | CTSL (0.69) | CTSLCTSSCTSKCTSBHTT | |
| SCHEMBL8200798 | 0.83 | CTSK (0.79) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL8236641 | 0.82 | CTSL (0.66) | CTSLCTSSCTSKCTSBHDAC6 | |
| SCHEMBL8241787 | 0.82 | CTSK (0.69) | CTSLCTSSCTSKCTSBHDAC1 | |
| SCHEMBL8243085 | 0.82 | CTSK (0.56) | CTSLCTSSCTSKCTSBHDAC3 | |
| SCHEMBL5791503 | 0.81 | CTSK (0.47) | CTSLCTSSCTSKCTSBHDAC3 | |
| Trifluoroacetic Acid SCHEMBL3169501 | 0.81 | CTSK (0.73) | CTSLCTSSCTSKCTSBHDAC6 | |
| SCHEMBL8245943 | 0.81 | L3MBTL1 (0.37) | CTSLCTSSCTSKCTSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025776-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |