Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12380356 | 1.00 | HIF1A (0.35) | HIF1ATSHRALDH1A1MAPTKISS1R | |
| SCHEMBL19415097 | 0.88 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL24084074 | 0.88 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL20799467 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1MAPTKISS1R | |
| SCHEMBL22538946 | 0.81 | ADH1B (0.42) | HIF1AKISS1R | |
| SCHEMBL12707399 | 0.81 | ADH1B (0.42) | HIF1AKISS1R | |
| SCHEMBL20342130 | 0.77 | — | — | |
| SCHEMBL14345861 | 0.77 | CA2 (0.43) | — | |
| SCHEMBL19003940 | 0.77 | ALDH1A1 (0.33) | ALDH1A1KISS1R | |
| SCHEMBL20342082 | 0.77 | KISS1R (0.33) | KISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342779-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2018-07-04 | — | — | EP | disclosed |
| WO-2006127948-A2 | N-TERMINALLY MODIFIED GLP-1 RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-11-30 | — | — | WO | disclosed |