Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6331409 | 0.87 | POLB (0.47) | SLC9A1HPGDGAAALDH1A1KDM4E | |
| SCHEMBL7395768 | 0.85 | GAA (0.54) | SLC9A1HPGDGAAALDH1A1KDM4E | |
| SCHEMBL23797026 | 0.77 | POLB (0.44) | SLC9A1HPGDGAAALDH1A1KDM4E | |
| SCHEMBL18669536 | 0.75 | ROCK2 (0.55) | HPGDGAAALDH1A1KDM4EGLA | |
| SCHEMBL25300381 | 0.73 | KDM4E (0.53) | HPGDGAAALDH1A1KDM4EGLA | |
| SCHEMBL7784015 | 0.73 | CUL4A (0.41) | SLC9A1HPGDGAAALDH1A1KDM4E | |
| SCHEMBL8007192 | 0.73 | GSK3A (0.40) | HPGDGAAALDH1A1KDM4EDRD2 | |
| SCHEMBL6826837 | 0.72 | CASP1 (0.43) | HPGDGAAALDH1A1KDM4EGLA | |
| SCHEMBL29361411 | 0.72 | NNMT (0.49) | HPGDALDH1A1KDM4ECASP1POLB | |
| SCHEMBL2527039 | 0.72 | NNMT (0.49) | HPGDALDH1A1KDM4ECASP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007005951-A2 | STEREOISOMERIC PYRIDYL AND PYRIDONYL COMPOUNDS AND METHODS FOR THE TREATMENT OF GASTROINTESTINAL AND CENTRAL NERVOUS SYSTEM DISORDERS | ARYX THERAPEUTICS, INC. (US) | 2007-01-11 | — | — | WO | disclosed |