Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12202714 | 0.90 | CSF1R (0.43) | CSF1R | |
| SCHEMBL8247686 | 0.87 | SOS1 (0.31) | — | |
| SCHEMBL8251777 | 0.78 | POLB (0.35) | TLR8 | |
| SCHEMBL8247680 | 0.77 | TLR8 (0.42) | CSF1RTLR8 | |
| SCHEMBL8251311 | 0.76 | TLR8 (0.42) | CSF1RTLR8 | |
| SCHEMBL8252433 | 0.75 | S1PR4 (0.36) | — | |
| SCHEMBL8250162 | 0.73 | ALDH1A1 (0.36) | CSF1RTLR8 | |
| SCHEMBL8251788 | 0.72 | CSF1R (0.36) | CSF1R | |
| SCHEMBL8251370 | 0.72 | EGFR (0.38) | — | |
| SCHEMBL8250136 | 0.71 | TRPC5 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006136561-A1 | 1- ( 2-AMINO-3- (SUBSTITUTED ALKYL)-3H-BENZIMIDAZOIYLMETHYL) -3-SUBTITUTED-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONES WITH ACTIVITY ON RESPIRATORY SYNCYTIAL VIRUS | TIBOTEC PHARMACEUTICALS LTD (IE) | 2006-12-28 | — | — | WO | disclosed |