Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL824782 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL824775 | 0.82 | ALDH1A1 (0.57) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL18417832 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL10400318 | 0.75 | MAPT (0.57) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL27885894 | 0.74 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL49467 | 0.74 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL974893 | 0.74 | MAPT (0.55) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL24795035 | 0.72 | ALDH1A1 (0.53) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| Hydrochloric Acid SCHEMBL31327345 | 0.72 | MAPT (0.53) | ALDH1A1MAPTL3MBTL1KCNH3CYP1A2 | |
| SCHEMBL4970157 | 0.72 | ALDH1A1 (0.89) | ALDH1A1MAPTL3MBTL1KCNH3HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143359-B2 | Organic silicone compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-03-27 | — | — | US | disclosed |
| US-20100160588-A1 | ORGANIC SILICONE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160588-A1 | ORGANIC SILICONE COMPOUND | OR10J3, FOXO1, OR51E2 | ALDH1A1 2040/4885MAPT 3529/4885L3MBTL1 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.