SCHEMBL824955

SCHEMBL824955

Nc1cccc2sccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.48
TSHR P16473 3/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
KEAP1 Q14145 1/20 0.41
ADRA2A P08913 1/20 0.41
ADRA2B P18089 1/20 0.41
CYP19A1 P11511 1/20 0.39
TBXAS1 P24557 1/20 0.39
NR4A2 P43354 1/20 0.38
CD44 P16070 1/20 0.36
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
ALOX15 P16050 1/20 0.35
CASP1 P29466 1/20 0.35
CASP7 P55210 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30176792 1.00 CYP3A4 (0.48) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL5153625 0.75 ADRA2A (0.56) ALDH1A1HPGDTDP1ADRA2AADRA2B
SCHEMBL8114338 0.73 ADRA2A (0.42) ALDH1A1HPGDTDP1ADRA2AADRA2B
SCHEMBL911513 0.71 ADRA2A (0.44) CYP3A4TSHRALDH1A1HPGDHSD17B10
SCHEMBL276421 0.71 ADRA2A (0.41) ADRA2AADRA2BCYP19A1TBXAS1SLC6A2
SCHEMBL24611290 0.71 ADRA2A (0.41) ALDH1A1HPGDTDP1ADRA2AADRA2B
SCHEMBL3791942 0.71 ADRA2A (0.44) ALDH1A1HPGDTDP1ADRA2AADRA2B
SCHEMBL289078 0.71 ADRA2A (0.41) ALDH1A1HPGDTDP1ADRA2AADRA2B
SCHEMBL827532 0.71 CYP1A2 (0.48) TSHRALDH1A1HPGDADRA2AADRA2B
SCHEMBL156152 0.71 CYP1A2 (0.48) ALDH1A1ADRA2AADRA2BCYP19A1TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240276856-A1 PREPARATION METHOD OF LIGHT-EMITTING DEVICE, LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS Beijing Boe Technology Development Co., Ltd. (CN) 2024-08-15 US claimed
CN-116649008-A Preparation method of light-emitting device, light-emitting device and light-emitting device 京东方科技集团股份有限公司 2023-08-25 CN claimed
WO-2023115259-A1 MANUFACTURING METHOD FOR LIGHT-EMITTING DEVICE, AND LIGHT-EMITTING DEVICE AND LIGHT-EMITTING APPARATUS 京东方科技集团股份有限公司 2023-06-29 WO claimed
CN-111205662-B Composite TB rubber powder modified asphalt 成都交通投资集团有限公司 2021-11-02 CN claimed
CN-109336469-B SBS modified asphalt mixture and preparation method thereof 湖北津泰环保科技有限公司 2021-06-08 CN claimed
CN-109486219-B Organic-coated nano titanium dioxide grafted SBS (styrene butadiene styrene) modified asphalt and preparation method thereof 湖北津泰环保科技有限公司 2021-04-30 CN claimed
CN-111410738-A Preparation method of amine autocatalytic polyether polyol 山东蓝星东大有限公司 2020-07-14 CN claimed
CN-111205662-A Composite TB rubber powder modified asphalt 成都交通投资集团有限公司 2020-05-29 CN claimed
EP-3520892-A1 CARRIER, ELECTRODE FOR FUEL CELL, MEMBRANE-ELECTRODE ASSEMBLY, AND FUEL CELL COMPRISING SAME Kolon Industries, Inc. (KR) 2019-08-07 EP claimed
CN-109988162-A One kind is according to piperazine Zole derivatives and preparation method thereof 武汉兴华智慧医药科技有限公司 2019-07-09 CN claimed
US-20190177309-A1 PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE AND INTERMEDIATES THEREOF CADILA HEALTHCARE LIMITED (IN) 2019-06-13 US claimed
CN-109486219-A A kind of organic coating nano-titanium dioxide grafting SBS modified asphalt and preparation method thereof 湖北津泰环保科技有限公司 2019-03-19 CN claimed
CN-109336469-A A kind of SBS modified asphalt mixture and preparation method thereof 湖北津泰环保科技有限公司 2019-02-15 CN claimed
CN-121801212-A Flame-retardant polystyrene particle and preparation method thereof 安徽昊源化工集团有限公司 2026-04-07 CN disclosed
CN-115894434-B Preparation method of 4-piperazinyl benzothiophene hydrochloride 山东厚德精诚药业有限公司 2024-10-08 CN disclosed
US-20240327432-A1 THIOPHENE-PHENOTHIAZINE COMPOUNDS AND SYNTHESIS METHOD THEREOF, AS WELL AS APPLICATION THEREOF IN PREPARATION OF PHOTOTHERAPY MEDICINES GUANGZHOU MEDICAL UNIVERSITY (CN) 2024-10-03 US disclosed
US-4514211-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
EP-0079683-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-05-25 EP disclosed
US-4191830-A HERBICIDES AND ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1980-03-04 US disclosed
US-4156670-A UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS AMERICAN CYANAMID COMPANY (US) 1979-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190177309-A1 PROCESS FOR THE PREPARATION OF BREXPIPRAZOLE AND INTERMEDIATES THEREOF CYP4Z1, CYP4X1, CYP4B1 CYP3A4 7/4885TSHR 2010/4885ALDH1A1 151/4885
US-20240327432-A1 THIOPHENE-PHENOTHIAZINE COMPOUNDS AND SYNTHESIS METHOD THEREOF, AS WELL AS APPLICATION THEREOF IN PREPARATION OF PHOTOTHERAPY MEDICINES ROS1, TYR, PPOX CYP3A4 96/4885TSHR 2652/4885ALDH1A1 550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.