Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 6/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 6/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11984813 | 0.92 | S1PR4 (0.39) | AGTR2S1PR4ACSS2AGTR1ALOX5AP | |
| SCHEMBL8252433 | 0.86 | S1PR4 (0.36) | AGTR2TLR7S1PR4AGTR1 | |
| SCHEMBL16327762 | 0.86 | AGTR2 (0.35) | AGTR2S1PR4ACSS2AGTR1ALOX5AP | |
| SCHEMBL8247680 | 0.85 | TLR8 (0.42) | TLR7 | |
| SCHEMBL8242374 | 0.83 | AGTR2 (0.39) | AGTR2TLR7AGTR1ALOX5AP | |
| SCHEMBL8248706 | 0.83 | HTT (0.46) | AGTR2AGTR1 | |
| SCHEMBL8242381 | 0.82 | TLR7 (0.35) | AGTR2TLR7S1PR4AGTR1ALOX5AP | |
| SCHEMBL8249741 | 0.82 | F2 (0.36) | AGTR2TLR7S1PR4AGTR1 | |
| SCHEMBL8251311 | 0.78 | TLR8 (0.42) | S1PR4 | |
| SCHEMBL16327722 | 0.75 | ALOX5AP (0.33) | AGTR2S1PR4ACSS2AGTR1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006136563-A1 | 2-SUBSTITUTED BENZIMIDAZOLES | TIBOTEC PHARMACEUTICALS LTD (IE) | 2006-12-28 | — | — | WO | disclosed |