Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23189343 | 0.82 | MC4R (0.34) | SLC6A3 | |
| SCHEMBL15081068 | 0.80 | ALDH1A1 (0.36) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL19251039 | 0.80 | — | — | |
| SCHEMBL12717192 | 0.80 | — | — | |
| SCHEMBL12717177 | 0.80 | — | — | |
| SCHEMBL8254468 | 0.79 | HRH3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| Iodide SCHEMBL16197417 | 0.78 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8515428 | 0.77 | FDPS (0.31) | SLC6A3SLC6A2SLC6A4 | |
| Iodide SCHEMBL10609626 | 0.76 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5327075 | 0.76 | LMNA (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006126081-A2 | PYRIDINO [2 , 3-B] PYRAZINONES AS PDE-5 INHIBITORS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-11-30 | — | — | WO | disclosed |